Radiotherapy Clinical Trials Advisory Service (RADCAS)

CTRad’s Workstream 3 has developed a process by which all new UK radiotherapy clinical trial proposals have access to a ‘Radiotherapy Clinical Trials Advisory Service’ (RADCAS) before submission to a funding body.

Investigators can approach the RADCAS team about any trial proposal in which radiotherapy is a significant component, to receive specialist advice on trial methodology, technical aspects of radiotherapy delivery, and biomarkers and translational research opportunities. RADCAS may be relevant to early phase as well as Phase III trials.

How to use RADCAS

This service is available at any time of the year, and supplements the opportunities for researchers to present and engage in interactive discussion at CTRad’s twice-yearly proposals guidance meetings.


You can download a guide below to find out more about this service, together with resources and contact for advice on different processes. If you want to use the RADCAS service, please contact the NCRI CTRad Team.

► Guide to using RADCAS, 2012 (PDF)

► CTRad’s twice-yearly proposals guidance meetings (NCRI webpage)

► Email the CTRad Team

Further information on trial development

► Checklist for components of a radiotherapy protocol, 2019 (PDF)

► Role of the clinical trials unit (CTU) – presentation by Emma Hall, October 2014 (PDF)

► Steps to successful trial launch – presentation by Emma Hall, May 2014 (PDF)